High Sensitivity Cardiac Troponin T

High sensitivity cardiac troponin testing.

Bösner and colleagues have presented evidence for a simple rule for ruling out coronary artery disease in the primary care setting. It is noteworthy that no laboratory measurements have been included in their model, with reference to their introductory statement that “ ... electrocardiography and cardiac troponin test are of limited value in primary care... ” This point deserves some discussion...

High-Sensitivity Cardiac Troponin T and Risk of Hypertension.

BACKGROUND The diagnosis of hypertension is often preceded by cardiac structural abnormalities. Thus, we assessed whether high-sensitivity cardiac troponin T (hs-cTnT), a marker of subclinical myocardial damage, can identify individuals at risk for hypertension or left ventricular hypertrophy. METHODS AND RESULTS We studied 6516 Atherosclerosis Risk in Communities (ARIC) Study participants wh...

Analytical validation of a high-sensitivity cardiac troponin T assay.

BACKGROUND We report the development of a novel high-sensitivity cardiac troponin T (hs-cTnT) assay, a modification of the Roche fourth-generation cTnT assay, and validation of the analytical performance of this assay. METHODS Validation included testing of analytical sensitivity, specificity, interferences, and precision. We established the 99th percentile cutoff from healthy reference popul...

High-sensitive cardiac troponin T

Cardiac troponin is the preferred biomarker for the diagnosis of acute myocardial infarction (AMI). The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits detection of very low levels of cTnT. Using the hs-cTnT assay improves the overall diagnostic accuracy in patients with suspected AMI, while a negative result also has a high negative predictive value. The gain ...

High-Sensitivity Cardiac Troponin T and Risk of Hypertension Running title: McEvoy et al.; High-sensitivity Troponin and Hypertension